Treatment of Depression

Lakshmi Yatham, MBBS, FRCPC, MRCPsych (UK), discusses treatment of depression.

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Lakshmi Yatham, MBBS, FRCPC, MRCPsych (UK), discusses treatment of depression.
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Featuring Dr. Lakshmi Yatham, MBBS, FRCPC, MRCPsych (UK)

Duration: 1 minute, 26 seconds


Approximately 60 percent of patients with depression respond to the first antidepressant that we prescribe, but the other 40 percent don’t respond.

In those situations, we’re trying to figure out what to do next. Some of the strategies that we use are switching patient from one antidepressant to a different antidepressant, perhaps to an antidepressant that belongs to a different class. For those that do not respond to the first antidepressant that we prescribe, we have number of strategies. One strategy would be to switch them to a different antidepressant, to an antidepressant that belongs to a different class. The other option is to add another medication to that antidepressant, and we call that an augmentation strategy.

The medications that we often use to augment are atypical antipsychotics or lithium; those are the two most common strategies. When we do that, another 30 to 50 percent of people respond, so it’s a pretty good strategy.

If you have more questions about how to treat refractory depression, please make sure to speak with you psychiatrist or a family physician.

Presenter: Dr. Lakshmi Yatham, Psychiatrist, Vancouver, BC

Local Practitioners: Psychiatrist

Video Quiz ( 19 participated.)

Test your knowledge by answering the following questions:

Questions True False  
1 Approximately 60% of depressed patients respond to the first medication they are prescribed.

 
2 Patients suffering from depression that don't respond to medication are often prescribed a second medication to try in combination with the first one, or they are switched to a different anti-depressant altogether.

 
3 When treating depression there are very few choices of medications that are safe and effective.

 

This content is for informational purposes only, and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare professional with any questions you may have regarding a medical condition.